Neurosarcoidosis

They can be multiple and diffuse. They are clinically observed in less than 10% of patients. They are associated in 80% of cases with an intrathoracic localization.

Neurosarcoidosis - Achieving meningitis

Achieving meningitis is the most classic. It is often asymptomatic. There is no specific modification of the LCR, but there is a higher protein and in approximately 50% of cases there is a elevation of the converting angiotensin enzyme. One can observe the scan or MRI enhancement of the pathological structures after contrast injection.

Neurosarcoidosis - Attacks on the central nervous system

Neurosarcoidosis attacks the central nervous system. They cover about 5% of sarcoidosis. The lesions are related to inflammatory granulomas development. The diversity of the substratum and their anatomical location explains the polymorphism of clinical manifestations: mental disorders, seizures, unusually symptoms which are associated with intramedullary lesions. Infiltration of the skull base by extending contiguous to the pituitary fossa, the hypothalamus, to the floor of the 3rd ventricle is responsible for neuro-endocrine signs.

Hypogonadism and insipidus diabetes are the most frequent. It may be may be associated with pituitary insufficiency and a hypothalamic insufficiency. Disturbances of the regulation of body temperature, behavioral type of binge food, disorders of the response against regulation to hypoglycemia have been reported.

Neurosarcoidosis pictures

Violations of the peripheral nervous system in Neurosarcoidosis

Violations of the peripheral nervous system. They are reported with a variable frequency depending on the series. It is usually a violation of cranial pairs but all types of neuropathy have been reported. The facial nerve is considered the most frequent case of neurosarcoidosis. It is either an infiltrative process or a compression process. It is a device but frequently associated with other central or peripheral neurological signs. It may be associated with Heerfordt syndrome.

All other cranial nerves can be achieved with less frequency and paralysis may be multiple. Arrays of symmetrical sensorimotor including the ulnar and sciatic external knee have been reported. In most cases these neuropathies are isolated, not linked to another attack or central meningitis.